How Does Cerenia Kill a Dog? Every Thing You Need To Know

Cerenia, scientifically known as Maropitant Citrate, is an essential drug in the field of canine health. Whether your dog suffers from motion sickness or is enduring the harsh aftermath of chemotherapy, Cerenia might be suggested by your veterinarian as a solution.

As responsible pet owners, it is crucial to understand the role, benefits, and potential side effects of any medication administered to our furry friends. This document aims to delve into the specifics of Cerenia, shedding light on its importance in maintaining the well-being of your canine companion.

In addition, we will also discuss the various conditions that Cerenia can help manage and its mode of action.

What is Cerenia and its Types?

Before diving into How Does Cerenia Kill a Dog, let us first understand what exactly Cerenia is. Cerenia belongs to a class of drugs known as neurokinin-1 (NK-1) receptor antagonists.

Cerenia is a medication primarily used in veterinary medicine to treat nausea and vomiting in dogs and cats. It belongs to a class of drugs called antiemetics, which work by blocking specific receptors in the brain associated with vomiting. Cerenia’s active ingredient is Maropitant citrate.

This medication is particularly effective in managing acute vomiting due to various causes such as motion sickness, chemotherapy-induced vomiting, and other gastrointestinal issues in pets.

It comes in different formulations, including injectable solutions and tablets, allowing for flexibility in administration based on the animal’s needs.

Moreover, Cerenia is also available in different strengths, ensuring that the appropriate dose is administered to your pet based on their weight and condition.

Types of Cerenia

There are a few types of Cerenia: Cerenia tablets and Cerenia injections. Both are used for different purposes.

1. Cerenia Tablets

Cerenia tablets come in four strengths – 16 mg and 24 mg 60 mg, and 160 mg, and they are typically given once a day to dogs who weigh more than 10 pounds.

This formulation is often used for the prevention of vomiting associated with motion sickness in dogs, making it an ideal choice for pet owners who enjoy traveling with their furry companions.

2. Cerenia Injection

Cerenia injection is typically administered by a veterinarian and is often used for the treatment of acute vomiting in dogs and cats. It comes in a single-use vial containing 10 mg/mL of Maropitant citrate.

This formulation is particularly helpful in managing vomiting caused by chemotherapy, metabolic diseases, and post-operative nausea.

The dosage of Cerenia varies depending on the animal’s weight, condition, and the severity of vomiting. It’s crucial to administer Cerenia as prescribed by a veterinarian and to follow their instructions carefully.

How does Cerenia work on Dogs?

Types of Cerenia

To understand how Cerenia works, it’s essential to know a little about the anatomy of a dog’s digestive system. The brain contains a vomiting center that receives sensory information from different areas of the body, such as the gastrointestinal tract and inner ear.

When this center receives signals indicating that something is not right in these areas (e.g., motion sickness), it triggers the act of vomiting to expel the harmful substance.

Mechanism of Action

Cerenia works by blocking neurokinin receptors in the central nervous system. Specifically, it antagonizes the neurokinin-1 (NK-1) receptor, which plays a significant role in triggering vomiting.

When a dog is exposed to a stimulus that induces vomiting (like motion sickness or gastrointestinal irritation), signals are sent to the vomiting center in the brain.

These signals involve the release of a neurotransmitter called substance P, which binds to NK-1 receptors, ultimately leading to the vomiting reflex.

Cerenia prevents substance P from binding to these receptors, effectively reducing the brain’s response to triggers that would otherwise cause vomiting. This mechanism of action makes Cerenia an effective and safe treatment for acute vomiting in dogs.

Duration of Action

The duration of action for Cerenia can vary between individual dogs and the specific condition being treated. Typically, Cerenia is available in various forms tablets, injectables, and oral solutions.

The injectable form tends to act more rapidly than oral administration. After oral administration, Cerenia reaches peak blood levels within a few hours and may provide relief from vomiting for approximately 24 hours.


Cerenia is generally considered an effective antiemetic (anti-vomiting) medication for dogs. It’s commonly used for various conditions that induce vomiting, including motion sickness during travel, nausea resulting from chemotherapy, gastrointestinal upset, and postoperative vomiting.

Its effectiveness can vary based on the underlying cause of vomiting, the individual dog’s response, and the dosage prescribed. In general, Cerenia has been proven to be a useful and safe treatment option for managing vomiting in dogs.

Possible Side Effects of Cerenia

Possible Side Effects of Cerenia

Cerenia is generally well-tolerated by most dogs with minimal side effects. However, as with any medication, there is always a risk of potential adverse reactions. Some of the most commonly reported side effects include:

  • Drowsiness: Some dogs may exhibit signs of drowsiness or lethargy after taking Cerenia. This side effect is typically mild and temporary, resolving as the medication wears off. Additionally, some dogs may become restless or agitated instead of feeling drowsy.
  • Diarrhea or Soft Stool: Gastrointestinal disturbances such as diarrhea or soft stool can occur in some dogs using Cerenia. This side effect may be transient and resolve without intervention.
  • Lack of Appetite: A temporary decrease in appetite can sometimes be observed in dogs on Cerenia. This usually resolves once the medication is discontinued.
  • Excessive Drooling: Some dogs may experience increased salivation or drooling, which is generally mild and temporary.
  • Vomiting: Paradoxically, although Cerenia is used to prevent vomiting, in rare cases, some dogs may experience vomiting as a side effect. This reaction is uncommon but can occur.
  • Lethargy: Some dogs may appear more lethargic than usual, experiencing a lack of energy or interest in activities. This side effect is generally mild and transient.
  • Allergic Reactions: While rare, allergic reactions to Cerenia can occur. Signs of an allergic reaction may include facial swelling, itching, hives, difficulty breathing, or collapse. Immediate veterinary attention is necessary if any of these symptoms develop.

It’s essential to pay close attention to any changes in your dog’s behavior or overall health while using Cerenia and report them to your veterinarian if they persist or worsen. Moreover, how Does Cerenia Kill a Dog is the question that comes to mind when discussing potential risks or side effects.

How Does Cerenia Kill a Dog?

How Does Cerenia Kill Dog

The question “How does Cerenia kill a dog?” might sound alarming. While Cerenia is designed to alleviate symptoms, like any medication, it’s essential to understand potential risks, especially if the prescribed dosage is exceeded or administered improperly. Here are some potential ways Cerenia can be harmful to a dog:

1. Overdose

An overdose of Cerenia can lead to toxicity and cause serious harm or even death. It’s vital to follow the prescribed dosage carefully and never exceed it without consulting a veterinarian.

This also applies to other medications that may interact with Cerenia, potentially increasing the risk of an overdose. In addition, it’s essential to store Cerenia in a safe place out of reach of pets, as accidental ingestion can also lead to overdose and toxicity.

2. Allergic Reaction

As mentioned earlier, an allergic reaction to Cerenia can occur in rare cases. If left untreated, a severe allergic reaction can lead to death due to anaphylactic shock.

It’s crucial to seek immediate veterinary attention if any signs of an allergic reaction are observed. Moreover, it’s also important to inform your veterinarian of any known allergies your dog may have before starting Cerenia treatment.

3. Interactions with Other Medications

Cerenia can interact with other medications, potentially causing adverse effects. It’s essential to inform your veterinarian of any other medications or supplements your dog is currently taking before starting Cerenia treatment. This includes over-the-counter drugs and herbal remedies.

4. Underlying Medical Conditions

Cerenia is not recommended for use in dogs with severe liver disease as it may worsen their condition. Additionally, the drug has not been tested in pregnant or nursing dogs and should be used with caution in these cases.

Safety Tips and Precautions When Using Cerenia

While Cerenia is generally considered safe for use in dogs, it’s important to follow certain precautions and safety tips to minimize the risk of adverse effects:

  • Follow Dosage Instructions: Always follow the prescribed dosage instructions provided by your veterinarian. Do not exceed the recommended dose without consulting a professional.
  • Store Safely: Keep Cerenia out of reach of pets and children. Store it in a secure place, away from direct sunlight and moisture.
  • Avoid Mixing with Other Medications: Do not mix Cerenia with other medications unless advised by your veterinarian. This includes over-the-counter drugs and supplements.
  • Watch for Side Effects: Keep an eye out for any potential side effects and report them to your veterinarian if they persist or worsen.
  • Disclose Medical History: Inform your veterinarian of any underlying medical conditions or allergies your dog may have before starting Cerenia treatment.
  • Seek Immediate Veterinary Attention for Allergic Reactions: If you suspect an allergic reaction, seek immediate veterinary attention.
  • Monitor Your Dog’s Response: Keep track of your dog’s response to Cerenia treatment and report any changes or concerns to your veterinarian.

By following these safety tips and precautions, you may mitigate the risk of How Does Cerenia Kill a Dog? So, it is essential to use Cerenia responsibly and under the guidance of a licensed veterinarian.

How to Administer Cerenia to Your Dog?

Cerenia is available in tablet form and as an injectable solution. It’s important to follow the instructions provided by your veterinarian for proper administration. Generally, it’s recommended to give Cerenia on an empty stomach at least one hour before or after a meal. This ensures better absorption of the medication.

If you’re administering Cerenia tablets, follow these steps:

  • Step 1: Prepare the Medication: Carefully remove the tablet from its packaging and handle it with clean hands to avoid contamination.
  • Step 2: Administer the Tablet: Place the tablet directly into your dog’s mouth or hide it in a small amount of food. Make sure your dog swallows the entire dose.
  • Step 3: Give Water: Offer your dog a small amount of water to help swallow the tablet if necessary.

If you’re administering Cerenia injectable solution, follow these steps:

  • Step 1: Prepare the Medication: Carefully remove the cap from the syringe and ensure that the needle is attached.
  • Step 2: Find a Suitable Injection Site: The recommended injection site for dogs is the scruff of the neck, where there’s loose skin and less muscle mass.
  • Step 3: Administer the Injection: Gently insert the needle under your dog’s skin at a 45-degree angle and press down on the plunger to release the medication.
  • Step 4: Remove Needle and Massage Injection Site: Once the injection is complete, remove the needle and massage the area to help distribute the medication.

It’s important to follow proper administration techniques to ensure that your dog receives the correct dosage and experiences maximum benefits from Cerenia treatment. If you have any concerns or questions about administering Cerenia, consult your veterinarian for guidance.

Bottom Line

Cerenia is a useful and effective medication for managing vomiting in dogs. However, it’s essential to use it carefully and follow the prescribed dosage instructions to avoid potential risks and adverse effects.

By understanding how Cerenia works, its potential side effects, and safety precautions, you can help your dog feel better and prevent further complications.

Remember, always consult with a professional before making any changes to your dog’s medication regimen, and closely monitor their response to treatment.

With proper care and treatment, you can help your furry friend feel better and improve their overall quality of life. So, if your dog is suffering from vomiting, talk to your veterinarian about Cerenia as a potential treatment option. Your furry companion will thank you!

To learn more about dogs, please visit our site and check out our different breed listings and guides to better understand your new canine companion.

We also offer a wide range of blogs about canine health, nutrition, exercise, behavior, and training tips to help keep your pup happy and healthy. Thanks for choosing us! Happy pet parenting!

Frequently Asked Questions

How Long Does Cerenia Take To Work With Dogs?

A: The onset of action for Cerenia varies depending on the form and dosage administered, but it typically starts working within an hour after ingestion.

Can I Give My Dog Cerenia For Motion Sickness?

A: Yes, Cerenia can be used to treat and prevent motion sickness in dogs. However, always consult with your veterinarian before giving any medication to your pet.

Q: Can I Give My Dog Cerenia on an Empty Stomach?

A: Cerenia is recommended to be given on an empty stomach at least one hour before or after a meal. This ensures better absorption of the medication.

Q: What Should I Do If My Dog Vomits After Taking Cerenia?

A: If your dog vomits within an hour of taking Cerenia, consult with your veterinarian for further instructions. They may advise you to give another dose or switch to a different treatment plan. Keep in mind that vomiting can also be a side effect of Cerenia, so it’s essential to monitor your dog closely and report any concerns to your veterinarian.

Disclaimer: Cerenia is a prescription medication and should only be used under the guidance and supervision of a licensed veterinarian. The information provided in this article is for educational purposes only and does not replace professional medical advice. Always consult with your veterinarian before making any changes to your dog’s treatment plan.—–

Avatar of Muhammad Naeem

I, am full-time writer and pet products researcher with more than 15 years professional experience in pet’s health & care including pet’s behavior and training. I, am also spent hours of time researching and testing different foods and brands for future dog parents who face food allergy or tolerance issues of their own.

Leave a Comment